KARL A TUPPER
1911 Oregon St., Berkeley, CA 94703 | karl.tupper [AT] aya.yale.edu
OBJECTIVE:
I am seeking intellectually changing work in the field of sustainability or alternative energy that will utilize my excellent analytical thinking skills.
EDUCATION:
M.S., Chemistry, University of California, Berkeley, 12/04. Research Adviser: T. Don Tilley
B.S., Chemistry, Yale University, New Haven, CT, 5/00. GPA: 3.6/4.0
EXPERIENCE:
Redefining Progress – Oakland, CA
Consultant to Sustainability Indicators Program, 1/06-present; Intern, 10/04-12/04.
--Performed global- and national-scale quantitative sustainability analyses using Ecological Footprint Analyses (EFA).
--Wrote macros in Visual Basic to streamline the generation EFA time series and comparisons of large numbers of countries.
--Generated times series data (1965-2001) for 160 countries for release on the RP’s forthcoming Footprint 2.0 website.
--Combed the EFA methodology (as implemented in Excel) and suggested improvements.
Sun Light & Power – Berkeley, CA
Biodiesel Maker, Warehouse Manager, and PV Installer 2, 12/04-present.
--Produced biodiesel for company vehicles from waste vegetable oil collected from local restaurants.
--Coordinated with local and state agencies to ensure that biodiesel production was conducted in a safe and environmentally friendly manner.
--Established and maintained oil collection relationships with local businesses.
--Operated, repaired, and modified biodiesel production equipment.
--Obtained building permits and attended inspections.
--Managed company warehouse, keeping it organized and stocked with various materials commonly used for PV, solar hot water, and radiant heating projects.
--Constructed rooftop photovoltaic arrays, solar hot water systems, and radiant heating installations.
The Princeton Review – Berkeley, CA
Organic Chemistry Instructor, 10/04-8/05.
--Led organic chemistry classes of up to 25 students.
University of California – Berkeley, CA
Graduate Student Researcher and Instructor, 9/01-12/04.
-Research Experience:
--Conducted original research in organometallic chemistry. Synthesized, characterized, and studied the reactivity of new and often highly unstable organoscandium complexes. Designed and synthesized new ligands for early transition metals.
--Mastered techniques for the manipulation of highly air and water sensitive compounds, including glove box and Schlenk-line techniques. Purified organic and inorganic compounds by standard methods including crystallization, chromatography, sublimation, and distillation.
--Characterized organic and organometallic compounds by NMR, IR, and UV/Vis spectroscopies, GC/MS, and melt point.
--Performed X-ray crystallographic analyses of single crystals.
--Authored, edited, and reviewed scientific papers.
-Teaching Experience:
--Three semesters supervising undergraduate teaching laboratories of up to 25 students.
--One semester assistant teaching graduate level courses (wrote and graded exams, quizzes and problem sets, held office hours.)
--Trained junior graduate students in Schlenk-line technique and instrumental analysis.
Abbott Laboratories – North Chicago, IL
QA Laboratory Technician, 10/00-8/01.
--Analyzed pre-release and stability drug samples in cGMP, FDA regulated laboratory.
--Performed dissolution assays, purity tests, Karl-Fischer titrations, and LODs.
--Prepared reagents and standard solutions in accordance with SOPs.
Pfizer Central Research – Groton, CT
Summer Intern/Student, Summers 1997-2000.
--Developed high throughput RP-HPLC based methods for the determination of lipophilicity (LogPoct and LogD-oct) of drug compounds. These methods have been patented and published and are now routinely used at Pfizer and other major pharmaceutical companies.
--Measured LogPoct and LogDoct of drug compounds by classical, shake-flask methods.
--Determined the solubility of drug molecules using HPLC quantitation techniques.
--Responsibilities also included HPLC method development and data analysis.
Yale University– New Haven, CT
-Undergraduate Researcher in the Hartwig Lab, Chemistry Dept., 1/99-5/00.
--Following published procedures, synthesized highly air and water sensitive organometallic compounds using dry box and Schlenk line techniques.
--Characterized compounds by IR and NMR spectroscopies and by GS/MS.
-Work Study in the Lasaga Lab, Geology Dept., 8/97-5/98.
--Duties included preparation of standard solutions and the spectrophotometric determination of aqueous Si and Al concentrations.
-Work Study in the Flavell Lab, Medical School, 9/96-5/97.
--Responsible for maintaining a large colony of transgenic tiger fish. Duties included preparation of standard solutions, setting brine shrimp cultures, fish feeding, and water testing.
AWARDS AND AFFILIATIONS:
Arthur Fleischer Research Award in Chemistry; Distinction in the chemistry major; High School Valedictorian, Bacon Academy (1996); American Chemical Society, 1999-2005.
SKILLS:
Organic, inorganic, and organometallic synthesis and characterization. Small molecule X-ray crystallography. cGMP Documentation. Basic construction and solar panel installation. Forklift operator. Mac and PC literate. Standard computer programs including Word, Excel, PowerPoint, and various web browsers. Programming in Visual Basic.
ACTIVITIES:
Performing Musicians' Co-operative, President (2/98-5/00); WYBC, disc jockey (9/99-5/00); Garbage Czar Record Company, staff member (2/99-6/01); Pearly Sweets & the Platonics, band member (2/98-7/01); Golden Birds, band member (6/03-present); Small-time concert promoter (9/97-5/00, 6/03-present.)
PUBLICATIONS AND PATENTS:
Tupper, K.A.; Tilley, T.D. “Synthesis and Characterization of Scandium Complexes With Reduced Ligands: Crystal Structures of Cp*ScI2, [Cp*ScI(bpy)]2, and [Cp*ScCl(bpy)]2” Journal of Organometallic Chemistry 2005, 690, 1689-1698.
Fontaine, F.-G.; Tilley, T. D.; Tupper, K. A. “Synthesis, Characterization and Reactivity of Tetramethylphospholyl Complexes of Scandium” Manuscript in Preparation.
Fuss, J.; Pierre, V.C.; Tupper, K.A. “Carbonyl (h5-pentamethylcyclopentadienyl)(triflato-O)(triisopropylphosphine-P)ruthenium(II). Acta Crystallographica 2002, E58, m482-m483.
Lombardo, F.; Shalaeva, M.Y.; Tupper, K.A.; Gao, F. “ElogDoct: A Tool for Lipophilicity Determination In Drug Discovery. 2. Basic and Neutral Compounds.” Journal of Medicinal Chemistry 2001, 44, 2490-2497.
Lombardo, F.; Shalaeva, M.Y.; Tupper, K.A.; Gao, F.; Abraham, M.H. “ElogPoct: A Tool for Lipophilicity Determination In Drug Discovery.” Journal of Medicinal Chemistry 2000, 43, 2922-2928.
Lombardo, F.; Shalaeva, M.Y.; Tupper, K.A. “ElogDoct: A Tool for Lipophilicity Determination In Drug Discovery. Basic and Neutral Compounds.” US Patent 2002 161 528, Oct. 31, 2002; European Patent 1 239 280, Sept. 9, 2002; Japanese Patents 2002 267 647, Sept. 18, 2002 and 3 444 872, Sept. 8, 2002.
Lombardo, F.; Shalaeva, M.Y.; Tupper, K.A. “Determination of logP coefficients via a RP-HPLC column.” US Patents 2002 009 388, Jan. 24, 2002 and 6 548 307, Apr. 15, 2003; European Patent 1 126 277, Aug. 22, 2001; Japanese Patent 2001 228 130, Aug. 24 2001.
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